Substituted 4-pyridone 3-carboxylic acid derivatives, method for

Details Substituted 4-pyridone 3-carboxylic acid derivatives, method for Substituted 4-pyridone 3-carboxylic acid derivatives, method for

1987-07-06

1991-09-03

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514249, 514291, 544349, 546 80, 546156, A61K 3147, C07D47104, C07D51304

Patent

active

050455494

ABSTRACT:
New 4-Pyridone derivatives of General Formula are claimed ##STR1## in which R.sub.1 is methylamino,4-fluorophenyl, 2,4-difluorophenyl, R.sub.2 is hydrogen or a sulfur atom that is joined to the ring nitrogen by an ethylene bride, X is a hydrogen or a physiologically removable ester group and Y is a base of the general formula ##STR2## In formula IIa and IIb, R.sub.3 is hydrogen, lower alkyl, benzyl, formyl, acetonyl or a moiety of the formula ##STR3## Also claimed are the addition salts of compounds of formula I with pharmaceutically acceptable inorganic or organic acids or base and/or their hydrates. Also claimed are the methods of manufacture of compounds of formula I and their use as antibacterial agents.

REFERENCES:
patent: 4292317 (1981-09-01), Pesson
patent: 4499091 (1985-02-01), Wentland et al.
patent: 4571396 (1986-02-01), Hutt et al.
patent: 4578473 (1986-03-01), Domagala et al.
patent: 4730000 (1988-03-01), Chu
patent: 4775668 (1988-10-01), Jefson et al.
patent: 4851418 (1989-07-01), Sanchez
patent: 4861779 (1989-08-01), Jefson et al.
patent: 4920120 (1990-04-01), Domagala et al.
patent: 4923879 (1990-05-01), Hutt, Jr. et al.
patent: 4962108 (1990-10-01), Hutt, Jr. et al.
patent: 4962112 (1990-10-01), Rosen et al.
Rosen et al., "The Design, Synthesis and Properties of A-65485 and Related Quinolone Antibacterial Agents", Abstract of the 1987 ICAAC (10/1987).

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