Method for inhibiting the development of tolerance in the analge

Details Method for inhibiting the development of tolerance in the analge Method for inhibiting the development of tolerance in the analge

1989-06-06

1991-08-20

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

A61K 31495

Patent

active

050414461

ABSTRACT:
Method for inhibiting the development of tolerance in the analgesic treatment with morphine of a subject in need of said treatment, comprising administering systemically and contemporarily an effective analgesic dose of morphine and an amount of dapiprazole of from 1/4 to 1 part by weight to 1 part by weight of said analgesic dose of morphine.
Pharmaceutical composition useful in the said method.

REFERENCES:
patent: 4252721 (1981-02-01), Silvestrini et al.

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