Physiologically active compositions of growth hormone and serum

Drug – bio-affecting and body treating compositions – Lymphokine

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514 12, 514 21, 530363, 530391, A61K 3736, A61K 3944, A61K 39395

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active

050453122

ABSTRACT:
Growth hormone is conjugated to any ligand, preferably a protein such as bovine serum albumin, optionally by use of a cross-linking agent such as a carbodiimide. The conjugates have enhanced activity when compared with unmodified growth hormone, and also better aqueous solubility at acid pH's.

REFERENCES:
patent: 3645852 (1972-02-01), Axen et al.
patent: 4003792 (1977-01-01), Mill et al.
patent: 4302386 (1981-11-01), Stevens
patent: 4464468 (1984-08-01), Avrameas et al.
Atassi et al., Biochimica et Biophysica Acta 670 (1981) pp. 300-302.
Carlsson et al., Biochem. J. 173, 1978, pp. 723-737.
Topper et al., Biochem. & Biophys. Res. Comm., 66(2): 793 (1975).
Molteni et al., Chem. Abstracts, 83: 48130h (1975).
Vonderhaar et al., Biochem. & Biophys. Res. Comm., 60(4): 1323 (1974).
Gestler et al., Chem. Abstracts, 102: 180588d (1985).
Mashita et al., Chem. Abstracts, 102: 40414n (1985).
Schepper et al., Chem. Abstracts, 101: 184415x (1984).
Cadwallader et al., Chem. Abstracts, 94: 180597X (1981).
Oka et al. (I), Science, 188: 1317 (1975).
Oka et al. (II), Proc. Nat. Acad. Sci., 71(5): 1630 (1974).
Wilchek et al. Proc. Nat. Acad. Sci., 72(3): 1055 (1975).
Dvorak et al., Ca vol. 89, 1978, #142819k.
Varner et al., Ca vol. 92, 1980, #161571b.
Fujii et al., Ca 103, 1985, #37724k.
Erba et al., Ca 89, 1978 #142889h.
Dovorak et al., Radiochem. Radioanal. Letters 34 (2-4) 155-160 (1978).

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