Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...
Patent
1979-01-04
1980-05-06
Rizzo, Nicholas S.
Organic compounds -- part of the class 532-570 series
Organic compounds
Nitrogen attached directly or indirectly to the purine ring...
424253, 544276, C07D47332
Patent
active
042018609
ABSTRACT:
Purine derivatives of the formula ##STR1## wherein R is C.sub.1 -C.sub.6 alkyl and R.sub.1 is ##STR2## and their pharmaceutically acceptable acid addition salts are non-adrenergic bronchodilators.
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Schaeffer et al., JACS vol. 81, 197-201 (1959).
Farmdoc (4-5-76), 70719y.
Farmdoc (12-10-75) 53190y.
Chem. Pharm. Bull. 23(4), 759-774 (1975).
Chem. Pharm. Bull. 25(7), 1811-1821 (1977).
Naito Takayuki
Nakagawa Susumu
Okita Taka-aki
Yamasaki Tetsuro
Yamashita Haruhiro
Bristol-Myers Company
Morse David M.
Rizzo Nicholas S.
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