Peptide substance restoring myocardium function

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

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Details

C530S330000

Reexamination Certificate

active

07662789

ABSTRACT:
The invention refers to the pharmaceutical means for the treatment of cardiovascular diseases and can be used as a substance restoring myocardium function in the course of treatment for different forms of this pathology.There is proposed a new tetrapeptide alanyl-glutamyl-aspartyl-arginine with general formula: Ala-Glu-Asp-Arg sequence 1 [SEQ ID NO:1], revealing biological activity, which is manifested in the restoration of the myocardium function.There is proposed a pharmacological substance containing an effective amount of tetrapeptide alanyl-glutamyl-aspartyl-arginine with general formula: Ala-Glu-Asp-Arg sequence 1 [SEQ ID NO:1] as an active peptide agent, revealing biological activity, which is manifested by the restoration of myocardium function. Being included in the medication, this substance contributes to the restoration of the myocardium function.

REFERENCES:
patent: 2032422 (1995-04-01), None
patent: 1417242 (1995-10-01), None
Actovegin,Register of Pharmaceutical Substances of Russia, Drug Encyclopedia, Moscow, 2003, pp. 63-64.
Amlodipine,Register of Pharmaceutical Substances of Russia, Drug Encyclopedia, Moscow, 2003, p. 90.
Dalargin,Register of Pharmaceutical Substances of Russia, Drug Encyclopedia, Moscow, 2003, p. 249.
Dobutamin,Register of Pharmaceutical Substances of Russia, Drug Encyclopedia, Moscow, 2003, p. 296.
Dopamine,Register of Pharmaceutical Substances of Russia, Drug Encyclopedia, Moscow, 2003, pp. 304-305.
Felodipine,Register of Pharmaceutical Substances of Russia, Drug Encyclopedia, Moscow, 2003, pp. 865-866.
Isosorbide,Register of Pharmaceutical Substances of Russia, Drug Encyclopedia, Moscow, 2003, p. 332.
Nitromint,Register of Pharmaceutical Substances of Russia, Drug Encyclopedia, Moscow, 2003, p. 587.
Nitrosorbide,Register of Pharmaceutical Substances of Russia, Drug Encyclopedia, Moscow, 2003, p. 588.
Pindolol,Register of Pharmaceutical Substances of Russia, Drug Encyclopedia, Moscow, 2003, pp. 659-660.
Propranolol,Register of Pharmaceutical Substances of Russia, Drug Encyclopedia, Moscow, 2003, pp. 700-701.
Verapamil,Register of Pharmaceutical Substances of Russia, Drug Encyclopedia, Moscow, 2003, p. 180.
Anisimov Sergey V. et al: “Elucidation of the effect of brain cortex tetrapeptide Cortagen on gene expression in mouse heart by microarray,” Neuro Endocrinology Letters, Feb.-Apr. 2004, vol. 25, No. 1-2, Feb. 2004, XP009046092, ISSN: 0172-780X—Abstract.
Database Biosis ′Online! Biosciences Information Service, Philadelphia, PA, US; 1992, Bakhtizina G. Z. et al: “Correction of tetramethylthiuram disulfide-induced damage to the myocardium by cardiac peptides,” XP002326898, Database accession No. PREV199395091835 abstract, and Patologicheskaya Fiziologiya i Eksperimental 'Naya Terapiya, vol. 0, No, 2, 1992, pp. 27-30, ISSN: 031-2991.
International Searching Authority, International Search Report and Written Opinion for International Application No. PCT/RU2004/000493 dated May 2, 2005.
Pavlenko V. S. (Reprint); Andreeva, L. I.; Ershov V. I.; Khavinson, V. K., Khlystov, V. V.: “Correlation between dose and pharmacological effects of cardiac peptides,” Bulletin of Experimental Biology and Medicine, vol. 114, No. 8, 1992, pp. 1144-1147, XP009046094.
Usynin, A. F. et al., “Ischemic myocardium damage and the influence of certain pharmacological substances on it in experimental rats,” Urgent Problems of Cardiology, Issue 2—Tomsk, Tomsk University Publishing, 1987, p. 116-118 (rus.).

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