Chiral integrin modulators and methods of use thereof

Organic compounds -- part of the class 532-570 series – Organic compounds – Sulfur containing

Reexamination Certificate

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C568S023000, C514S707000, C514S708000

Reexamination Certificate

active

07045663

ABSTRACT:
The invention provides enantiomers of ajoene and derivtives of Z(−)-ajoene. The derivative of Z(−)-ajoene are useful for modulating integrin-mediated functions, for treating disorders, diseases or conditions in which integrins play a role, and for treating tissues to improve their condition for a subsequent use, such as transplantation.

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