Vascular endothelial growth factor 2

Details Vascular endothelial growth factor 2 Vascular endothelial growth factor 2

1997-12-24

1999-08-03

Ulm, John

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

530326, 530399, 530402, A61K 3814, C07K 14475

Patent

active

059325402

ABSTRACT:
Disclosed are human VEGF2 polypeptides, biologically active, diagnostically or therapeutically useful fragments, analogs, or derivatives thereof, and DNA(RNA) encoding such VEGF2 polypeptides. Also provided are procedures for producing such polypeptides by recombinant techniques and antibodies and antagonists against such polypeptides. Such polypeptides may be used therapeutically for stimulating wound healing and for vascular tissue repair. Also provided are methods of using the antibodies and antagonists to inhibit tumor angiogenesis and thus tumor growth, inflammation, diabetic retinopathy, rheumatoid arthritis, and psoriasis.

REFERENCES:
patent: 5073492 (1991-12-01), Chen et al.
patent: 5219739 (1993-06-01), Tischer et al.
patent: 5326695 (1994-07-01), Andersson et al.
patent: 5607918 (1997-03-01), Eriksoon et al.
Eichmann, A., et al., Development 125(4):743-752 (1998).
Pajusola, K., et al., Cancer Research. 52:5738-5743 (1992).
Pajusola, K., et al., Oncogene 8:2931-2937 (1993).
Tischer, et al., Biochemical and Biophysical Research Communications 165(3):1198-1206 (1989).
Leung, D.W., et al., Science 246:1306-1309 (1989).
Breier, G., et al., Development 114:521-532 (1992).
Ferrara, et al., Journal of Cellular Biochemistry 47:211-218 (1991).
George et al., Macromolecular Seq. and Syn. Selected Meth--Application, pp. 127-149 (1988).

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