Tricyclic diazepine vasopressin antagonists and oxytocin antagon

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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540542, 540561, C07D22300, C07D48712, A61K 3155

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active

057339058

ABSTRACT:
Tricyclic diazepines of the formula: ##STR1## wherein A, B, D, E, F, Y and Z are defined in the specification which compounds have vasopressin and oxytocin antagonist activity.

REFERENCES:
Chemical Abstract 123: 228225 for EP 636625 (Feb. 1, 1995) , Albright.
Yamamura et al., Science, 252, pp. 572-574 (1991).
Yamamura et al., Br. J. Pharmacol., 105, pp. 787-791 (1992).

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