Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Patent
1994-08-29
1997-07-15
Cook, Rebecca
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
514423, 514645, A61K 31195, A61K 3113
Patent
active
056483937
ABSTRACT:
Methods of relaxing corpus cavernosum smooth muscle, treating disease states responsive to prevention or relaxation of undesirable contractions of corpus cavernosum smooth muscle and of treating male impotence by administering an S-nitrosothiol such as a low molecular weight S-nitrosothiol, S-nitroso-ACE-inhibitor or S-nitroso-protein.
REFERENCES:
patent: 5002964 (1991-03-01), Loscalzo et al.
patent: 5025001 (1991-06-01), Loscalzo et al.
Rajfer et al, Nitric Oxide as a Mediator, NEJM, 326/2 Jan. 9, 1992, pp. 90-94.
Morales et al, Word J. Urol (1990) 8:80-83.
Brown Robert
Drazen Jeffrey
Loscalzo Joseph
Simon Daniel
Slivka Adam
Brigham & Women's Hospital
Cook Rebecca
Herron Charles J.
Olstein Elliot M.
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