Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2005-03-18
2009-02-24
Shiao, Rei-tsang (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S444000, C514S471000, C549S075000, C549S059000, C549S494000
Reexamination Certificate
active
07495023
ABSTRACT:
The present invention relates to thio semicarbazone and semicarbazone inhibitors of cysteine proteases and methods of using such compounds to prevent and treat protozoan infections such as trypanosomiasis, malaria and leishmaniasis. The compounds also find use in inhibiting cysteine proteases associated with carcinogenesis, including cathepsins B and L.
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Cohen Fred E.
Du Xiaohui
Guo Chun
McKerrow James H.
Shiao Rei-tsang
The Regents of the University of California
Townsend and Townsend / and Crew LLP
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