Therapeutic agents

Drug – bio-affecting and body treating compositions – Lymphokine

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Details

514557, A61K 3119, A61K 3178

Patent

active

047864958

ABSTRACT:
A pharmaceutical composition comprising the analgesic and anti-inflammatory agent 2-(2-fluoro-4-biphenylyl)propionic acid or a pharmaceutically acceptable salt thereof and certain esters of natural vegetable oil fatty acids, provides a rapid release of 2-(2-fluoro-4-biphenylyl)propionic acid into the body, and hence a very rapid analgesic and anti-inflammatory effect.

REFERENCES:
patent: 3288824 (1966-11-01), Mahler et al.
patent: 3966978 (1976-06-01), Ellenbogen et al.
patent: 4388307 (1983-06-01), Cavanak
patent: 4473584 (1984-09-01), Heckler
patent: 4477468 (1984-10-01), Heckler
patent: 4514386 (1985-04-01), Yamahira et al.
patent: 4543251 (1985-09-01), Kamishita
Chem. Abstracts vol. 103, No. 20, p. 360, 166015d.
Chem. Abstracts vol. 105, p. 368, 66339k.
Chem. Abstracts vol. 105, p. 730, 158757y.
Gelucire Trade Literature "Gelucire Puts Liquid Formulations Into Hard Gelatin Capsules".
"Gelucire--Excipients for Hard Gelatin Capsules" Gelucire--BTG No. 74-1981.
The Filling of Molten and Thixotropic Formulations into Hard Gelatin Capsules. (J. Pharm. Pharmacol. 1980, 32, p. 389-393).
Diffusion and Erosion Controlled Drug Release From Lipid Matrix Formulations Incorporated into Hard Gelatin Capsules.
Derwent Abstract 80-87365 c/49.
Derwent Abstract 23213 k/10.
Derwent Abstract 86-123464/19.
Derwent Abstract 85-211497/35.
Derwent Abstract 81-87958 D/48.

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