Substituted 2H-pyran-2,6(3H)-dione derivatives, pharmaceutical c

Drug – bio-affecting and body treating compositions – Nonspecific immunoeffector – per se ; or nonspecific... – Lipid or oil

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2603459, A61K 3135, C07D30920

Patent

active

040326527

ABSTRACT:
Substituted 2H-pyran-2,6(3H)-dione derivatives, pharmaceutical compositions comprising such derivatives and methods of inhibiting the antigen-antibody reaction by administering said compositions. The active ingredients are the products formed by the reaction of acetonedicarboxylic acid with acetic anhydride followed by reaction with an appropriate amine. Certain of the dione derivatives are novel compounds per se.

REFERENCES:
patent: 3849565 (1974-11-01), Pfister et al.
patent: 3864493 (1975-02-01), Cairns et al.
patent: 3879544 (1975-04-01), Reisner et al.
Physician's Desk Reference (PDR), 1974, 28th Edition, pp. 760-761.
R. H. Wiley et al., J. Org. Chem. 21, 686-688, (1956).
A. K. Kiang et al., J. Chem. Soc. (C), 2721-2726, (1971).

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