Substituted 2-(heteroaryl-2-propenyl)phenols useful as anti-infl

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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548337, 548343, 548535, 548543, 548560, 548251, 548252, 548253, 548335, 549 51, 549 58, 549 78, 549471, 549475, 549484, 549491, 549497, 549501, 549502, 514277, 514345, 514381, 514398, 514399, 514424, 514427, 514438, 514443, 514445, 514448, 514461, 514469, 514473, 546298, 546301, 546326, 546330, 546344, A61K 3140, C07D20734

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active

047788186

ABSTRACT:
Substituted cinnamyl-2,3-dihydrobenzofurans and analogs were prepared from the nucleophlic substitution of a cinnamylhalide with a 2,3-dihydrobenzofuran anion or an analog thereof. These compounds were found to be potent topical anti-inflammatory agents.

REFERENCES:
Hurd et al., J.A.C.S., vol. 59, pp. 107-109 (1937).

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