Substituted [(2,3-dihydro-1-oxo-1H-inden-5-yl)amino]alkanoic aci

Details Substituted [(2,3-dihydro-1-oxo-1H-inden-5-yl)amino]alkanoic aci Substituted [(2,3-dihydro-1-oxo-1H-inden-5-yl)amino]alkanoic aci

1985-08-02

1986-04-01

Reamer, James H.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Radical -xh acid, or anhydride, acid halide or salt thereof...

560 43, 562456, 562457, 514534, C07C10178, A61K 31195

Patent

active

045798699

ABSTRACT:
The invention relates to novel substituted [(2,3-dihydro-1-oxo-1H-inden-5-yl)amino]alkanoic acids, their derivatives and their salts. The compounds are useful for the treatment and prevention of injury to the brain and of edema due to head trauma, stroke (particularly ischemic), arrested breathing, cardiac arrest, Reye's syndrome, cerebral thrombosis, cerebral embolism, cerebral hemorrhage, cerebral tumors, encephalomyelitis, spinal cord injury, hydrocephalus, post-operative brain injury trauma, edema due to cerebral infections and various brain concussions.

REFERENCES:
patent: 3954852 (1976-05-01), Shen et al.
patent: 4081554 (1978-03-01), Cragoe et al.
patent: 4096267 (1978-06-01), Cragoe et al.
patent: 4148916 (1979-04-01), Payne
patent: 4249021 (1981-02-01), Cragoe et al.

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