Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1997-11-18
1999-02-23
Huang, Evelyn
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546201, A61K 31445, C07D40104
Patent
active
058744487
ABSTRACT:
1-Oxo-2-(2,6-dioxo-3-fluoropiperidin-3-yl)isoindolines and 1,3-dioxo-2-(2,6-dioxo-3-fluoropiperidin-3-yl)isoindolines reduce the levels of TNF.alpha. in a mammal. A typical embodiment is 1,3-dioxo-2-(2,6-dioxo-3-fluoropiperidin-3-yl)-isoindoline.
REFERENCES:
patent: 5385901 (1995-01-01), Kaplan
patent: 5635517 (1997-06-01), Muller
patent: 5798368 (1998-08-01), Muller
Chen Roger Shen-Chu
Man Hon-Wah
Muller George W.
Stirling David I.
Celgene Corporation
Huang Evelyn
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