Substituted 1,3,4,9-tetrahydropyrano(3,4-B)indole-1-acetic acids

Details Substituted 1,3,4,9-tetrahydropyrano(3,4-B)indole-1-acetic acids Substituted 1,3,4,9-tetrahydropyrano(3,4-B)indole-1-acetic acids

1986-03-11

1987-06-02

Ceperley, Mary E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548432, A61K 3140, C07D49304

Patent

active

046704620

ABSTRACT:
Indole derivatives characterized by having a 1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid nucleus bearing a substituent in position 1 and 4. The nucleus may be optionally substituted at positions 5, 6, 7 and 8. The derivatives are useful anti-inflammatory and analgesic agents and methods for their preparation and use are also disclosed.

REFERENCES:
patent: 3843681 (1974-10-01), Demerson et al.
patent: 3939178 (1976-02-01), Demerson et al.
patent: 3974179 (1976-08-01), Demerson et al.
patent: 4003913 (1977-01-01), Demerson et al.
patent: 4012417 (1977-03-01), Demerson et al.
patent: 4070371 (1978-01-01), Demerson et al.
patent: 4076831 (1978-02-01), Demerson et al.
Derwent Abstract of European Patent 5365, published 11/1979.
Derwent Abstract of U.S. Patent 4,066,780 issued 1/1978.
Derwent Abstract of U.S. Patent 4,066,779 issued 1/1978.
Derwent Abstract of U.S. Patent 4,041,169 issued 8/1977.
Derwent Abstract of U.S. Patent 4,021,451 issued 5/1977.
Derwent Abstract of U.S. Patent 3,880,853 issued 4/1975.
Derwent Abstract of Netherlands Patent 7,300,518, published 7/1973.
Derwent Abstract of German Patent DE 2301525, published 7/1973.

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