Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant...
Patent
1985-04-10
1988-01-26
Lovering, Richard D.
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
264 41, 264 46, 424 71, 424450, 4284022, 436 52, 436829, 514 78, 514167, 514887, 514967, A61J 307, A61K 952, A61K 4300, B01J 1302
Patent
active
047216123
ABSTRACT:
Methods and compositions are described for the preparation of lipid vesicles, the bilayers of which comprise a salt form of an organic acid derivative of a sterol such as the tris-salt form of a sterol hemisuccinate. The method is rapid, efficient, and does not require the use of organic solvents. The sterol hemisuccinate vesicles may be used to entrap compounds which are insoluble in aqueous solutions. Such preparations are especially useful for entrapping bioactive agents of limited solubility thus enabling administration in vivo.
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Bolcsak Lois E.
Janoff Andrew S.
Popescu Mircea C.
Tremblay Paul S.
Weiner Alan L.
Bloom Allen
Lovering Richard D.
Saunders Thomas M.
The Liposome Company Inc.
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