Renin inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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Details

514218, 5142275, 5142312, 5142388, 544 60, 544133, 544139, 544140, 544159, 544369, 544370, 544371, 540575, A61K 31495, A61K 3155, C07D40300, C07D41300

Patent

active

052848493

ABSTRACT:
A renin inhibiting compound of the formula: ##STR1## wherein R.sub.1 is 4-piperazinyl, 1-methyl-4-piperazinyl, 1-methyl-1-oxo-4-piperazinyl, 2-oxo-4-piperazinyl, 4-morpholinyl, 4-thiomorpholinyl or 1-methyl-4-homopiperazinyl;

REFERENCES:
patent: 4812442 (1989-03-01), Boger et al.
patent: 4845079 (1989-07-01), Luly et al.
patent: 4906613 (1990-03-01), Watkins et al.
patent: 4927807 (1990-05-01), Stein et al.
patent: 5122514 (1992-06-01), Boger et al.
patent: 5122523 (1992-06-01), Morishima

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