Reduction of blood pressure with carboxyalkylacyl-pipecolic acid

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...

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546221, 546226, 546242, 546245, A61K 31445

Patent

active

041286537

ABSTRACT:
New carboxyalkylacylamino acids which are derivatives of proline, pipecolic acid and azetidine-2-carboxylic acid and have the general formula ##STR1## are useful as angiotensin converting enzyme inhibitors.

REFERENCES:
patent: 2627487 (1953-02-01), Drake et al.
patent: 3335145 (1967-08-01), Cislak et al.
Shriner, R. et al., The Systematic Identification of Organic Compounds, 3rd Ed., John Wiley and Sons, NY, 1948, p. 154.
Martin, E. W., (Editor), Husa's Pharmaceutical Dispensing, Fifth Ed., Mack Publishing Co., Easton, Pa., 1959, pp. 583-584.

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