Drug – bio-affecting and body treating compositions – Dentifrices
Patent
1982-06-11
1985-08-27
Jones, Raymond N.
Drug, bio-affecting and body treating compositions
Dentifrices
426548, 426549, 426590, 426650, 426660, 426658, 426804, 435 97, 536 181, 424 64, A61K 716, A23L 1236, C12P 1918, C07H 300
Patent
active
045377634
ABSTRACT:
New .alpha.-glycosyl glycyrrhizins bearing two or more .alpha.-glucose residues are prepared. Such .alpha.-glycosylation is carried out by subjecting an aqueous solution of glycyrrhizin (or a salt thereof) and an amylaceous substance (e.g. starch or cyclodextrin) to the enzymatic action of an .alpha.-glycosyl transferase (e.g. cyclodextrin glucanotrasferase). The .alpha.-glycosyl glycyrrhizins are low-caloric, low-cariogenic, mild, non-bitter, non-lingering sweeteners which may be advantageously incorporated into foods, beverages, cosmetics, dentifrices and drugs.
REFERENCES:
patent: 3878191 (1975-04-01), Fukumoto et al.
patent: 3923598 (1975-12-01), Horikoshi
patent: 3988206 (1976-10-01), Shiosaka
patent: 4135977 (1979-01-01), Horikoshi
patent: 4219571 (1980-08-01), Miyake
patent: 4393200 (1983-07-01), Miyashita et al.
Inglett, George E.; Symposium: Sweeteners, AVI Publishing Co., Inc., Westport, Conn., 1974, Chs. 19 & 20.
Chemical Abstracts, 57000t, vol. 83, p. 359 (1975).
Bender, H., "Cyclodextrin-Glucanotransferase von Klebsiella pneumoniae", Arch. Microbiol., 111, pp. 271, 282 (1971).
Hijiya Hiromi
Miyake Toshio
Jones Raymond N.
Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo
Weimar Elizabeth C.
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