Process for preparing 4-substituted imidazole compounds

Details Process for preparing 4-substituted imidazole compounds Process for preparing 4-substituted imidazole compounds

1978-06-14

1980-07-29

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

548315, 548316, 548336, 548337, 548342, 546210, C07D23364, C07D23384, C07D40106, C07D41306

Patent

active

042152178

ABSTRACT:
A process for preparing 4-(oxy, thio or amino)methylimidazole compounds via displacement of the trisubstituted phosphonium group from 4-(trisubstituted phosphonium)-methylimidazole compounds is disclosed.

REFERENCES:
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patent: 3325546 (1967-06-01), Hays
patent: 4104472 (1978-08-01), Labaw et al.
Houben-Weyl, Methoden der Organischen Chemie, vol. XXI, Part I, p. 51, (1963).
Berlin et al., Chem. Review 1960, vol. 60, pp. 247-248.
Aksnes et al., Chem. Abst., 1962, vol. 57, pp. 14473-14474.
Allen et al., Chem. Abst., 1974, vol. 80, No. 47138t.
Grayson et al., J.A.C.S. 1959, vol. 81, pp. 4803-4807.
House, Modern Synthetic Reactions, pp.701-702, W. A. Benjamin, 1972.
Organic Reactions, v. 14, pp. 278-279, N.Y. Wiley, 1965.
Zbiral et al., Teltrahedron Letters, 1972, No. 5, pp. 439-444.
Zbiral et al., Phosphorus 1972, vol. 2, pp. 29-34.
Zbiral, Synthesis 1974, vol. 11, pp. 775-797.

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