Preparation of quinoline derivatives

Details Preparation of quinoline derivatives Preparation of quinoline derivatives

1975-09-05

1978-05-30

Daus, Donald G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260289H, C07D21520

Patent

active

040923177

ABSTRACT:
A new process for preparing 5-oxo-tetrahydroquinolines comprises condensing a compound of formula II with a ##STR1## compound of formula III to obtain a compound of formula I wherein R, R.sup.1, R.sup.2 and R.sup.3 are selected from hydrogen and lower alkyl. Compounds of formula I are intermediates for pharmaceuticals.

REFERENCES:
Bowden, et al., J. Chem. Soc., (1946), pp. 945-948.
Sholdinov, et al., "Chem. Abstracts," 56, p. 3359b, (1962).
Elderfield, "Heterocyclic Compounds," vol. 4, pp. 36 and 37, (1952), Wiley, N.Y.

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