Platelet-activating factor acetylhydrolase (PAF-AH) therapeutic

Drug – bio-affecting and body treating compositions – Enzyme or coenzyme containing – Hydrolases

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435195, 435196, 435197, A61K 3846, C12N 918, C12N 916, C12N 914

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active

060998369

ABSTRACT:
The present invention provides purified and isolated polynucleotide sequences encoding human plasma platelet-activating factor acetylhydrolase. Also provided are materials and methods for the recombinant production of platelet-activating factor acetylhydrolase products which are expected to be useful in regulating pathological inflammatory events. Specifically disclosed are methods for the treatment of reperfusion injury using platelet-activating factor acetylhydrolase products.

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