Pharmaceutical piperidine derivatives

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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424246, 424250, 424251, 424267, 424273R, 424285, 424317, A61K 3133

Patent

active

040753352

ABSTRACT:
Piperidines of the formula ##STR1## in which R.sub.1 stands for optionally substituted aryl, R.sub.2 for hydrogen, lower alkyl, lower alkenyl, acyl or .alpha.-aryl-lower alkyl, R.sub.3 for a free or substituted hydroxyl group, alk for lower alkylene which separates the two nitrogen atoms by 2 or 3 carbon atoms, R.sub.4 represents hydrogen or lower alkyl and n represents an integer from 1 to 4, and their salts as well as processes for their manufacture and pharmaceutical compositions comprising such compounds, and a process for lowering the blood pressure wherein such compositions are administered to a warm-blooded host.

REFERENCES:
patent: 3318900 (1967-05-01), Janssen
patent: 3459757 (1969-08-01), Wright et al.
patent: 3956335 (1976-05-01), Wilhelm et al.
patent: 3969518 (1976-07-01), Novello

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