Pharmaceutical active 1,2,3,4,4A,5,10,10A-octahydrobenzo[g] quin

Details Pharmaceutical active 1,2,3,4,4A,5,10,10A-octahydrobenzo[g] quin Pharmaceutical active 1,2,3,4,4A,5,10,10A-octahydrobenzo[g] quin

1985-11-13

1987-09-08

Rizzo, Nicholas S.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546101, A61K 3147, C07D22108

Patent

active

046924531

ABSTRACT:
A 6- or 8-monooxy- or 6,8-dioxy-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinoline in which the 3-position is unsubstituted, is useful as a pharmaceutical, in particular as a prolactin secretion inhibitor, dopaminergic agent and dopamine receptor stimulating agent.

REFERENCES:
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patent: 4565818 (1986-01-01), Nordmann et al.
Walsh et al., J. Org. Chem., vol. 39, No. 25, pp. 3705-3708 (1974).
Cannon et al., Chemical Abstracts, vol. 92, 51846n (1980).
Cannon et al., Chemical Abstracts vol. 94, 83909t (1981).
Costall et al., Chemical Abstracts, vol. 95, 161968y (1981).
Cannon et al., Chemical Abstracts, vol. 96, 6539m (1982).
Maixner et al., Chemical Abstracts, vol. 98, 172567e (1983).
Cannon et al., Chemical Abstracts, vol. 100, 51426j (1984).

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