Novel arylcycloalkanepolyalkylamines

Details Novel arylcycloalkanepolyalkylamines Novel arylcycloalkanepolyalkylamines

1990-07-31

1992-02-04

Richter, Johann

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

5142375, 5142378, 5142382, 5142388, 514317, 514319, 514320, 514323, 514326, 514422, 514423, 514424, 514427, 544158, 544160, 544161, 544164, 548527, 548530, 548537, 548538, 548539, 548541, 548542, 548543, 548205, 548198, 548196, 548201, 546208, 546212, A61K 31445, A61K 3133, C07D26530, C07D29522, C07D21106

Patent

active

050860542

ABSTRACT:
Novel arylcycloalkanepolyalkylamines useful as anti-psychotic, anti-ischemia, anti-stroke, anti-dementia and anti-convulsant agents. These arylcycloalkanepolyalkylamines are selective high-affinity ligands to the sigma binding-sites containing three basic units: arylcycloalkyl group, an amine group and an intermediate chain. Their preparation and use for treatment of psychoses, ischemia, stroke, dementia and convulsions are also disclosed.

REFERENCES:
patent: 4634713 (1987-01-01), Werner et al.

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