Naphthyridine antibacterial agents containing an .alpha.-amino a

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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540579, 544349, 544362, 544363, 546123, 546126, 546156, A61K 3144, C07D47104

Patent

active

048514187

ABSTRACT:
Novel quinolone and naphthyridine antibacterial agents are herein described having improved in vivo activity both orally and subcutaneously where the 7-side chain of such compounds contain an .alpha.-amino acid; also described are its corresponding optical isomers, methods of preparation as well as compositions and methods of treating infections diseases.

REFERENCES:
Egawa et al., J. Med. Chem., vol. 27, pp. 1543-1548, (1984).

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