Chemistry: electrical and wave energy – Processes and products – Processes of treating materials by wave energy
Patent
1970-11-12
1976-03-02
Williams, Howard S.
Chemistry: electrical and wave energy
Processes and products
Processes of treating materials by wave energy
21 54R, 21102R, 21DIG2, 2041571R, 20415911, 204162R, 204DIG11, 426237, A21D 600, A61L 100, B01J 110
Patent
active
039416704
ABSTRACT:
A method of altering (i.e., deactivating or activating) the biological activity of macromolecular species that employs laser beam radiation at a frequency that excites vibrational and rotational states of the irradiated species and at an intensity sufficient to activate the species (but below the denaturation level) or to a level such that the weak bonds-- e.g., hydrogen bonds--that determine the spatial character, and hence the biological activity of macromolecules are irreversibly broken to such extent that the macromolecule loses its original form (the process of denaturation) and assumes an inactive (denatured) configuration. The latter is a sterilization or inactivating process and for such sterilization the macromolecular species may be disposed on a highly reflecting surface, such as a metal, which reflects the beam and is capable of amplifying the destructive characteristic, or upon absorbing surfaces, such as plastics, cloth or paper which ordinarily would be destroyed by the beam. In the case of absorbing materials, pulses of energy from the beam, which are obtained by interrupting a c.w. beam, using a pulsed laser, or as a Q-switched configuration, are used so as to deactivate the macromolecular species of interest but not to damage significantly the absorbing material. The invention is also directed to the sterilization of air and other gases as well as liquids and is accomplished by exposing these vapors or fluids to the beam.
REFERENCES:
patent: 3233964 (1966-02-01), Skoldberg
patent: 3600291 (1971-08-01), Wiley
patent: 3702973 (1972-11-01), Daugherty et al.
patent: 3719454 (1973-03-01), Shang
patent: 3817703 (1974-06-01), Atwood
McGuff et al., Medical & Biological Illustration, Vol. 16 (1966), pp. 191-194.
Elion, Laser Systems & Applications (1967), pp. 79-81.
Electronics, Vol. 34, Nov. 24, 1961, pp. 54-57.
Nature, No. 4965 (Dec. 16, 1964), p. 1295.
Massachusetts Institute of Technology
Santa Martin M.
Shaw Robert
Smith, Jr. Arthur A.
Williams Howard S.
LandOfFree
Method of altering biological and chemical activity of molecular does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method of altering biological and chemical activity of molecular, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of altering biological and chemical activity of molecular will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1276727