Method and compounds for the inhibition of adenylyl cyclase

Details Method and compounds for the inhibition of adenylyl cyclase Method and compounds for the inhibition of adenylyl cyclase

1998-05-04

2000-10-17

Knode, Marian C.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

536 2621, 536 2623, 536 2626, 536 267, 544264, 435183, 435184, C12N 900, C07H 1920, C07D47300

Patent

active

061329576

ABSTRACT:
The present invention reveals a new series of derivatives and analogues of adenine and adenosine, i.e., 3'-adenosine derivatives, which inhibit adenylyl cyclase activity. These newly synthesized compounds include the most potent inhibitors of adenylyl cyclases known. The present invention also discloses a method for measuring the inhibition of adenylyl cyclase activity.

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