Medicament for preventive and/or therapeutic treatment of hyperp

Details Medicament for preventive and/or therapeutic treatment of hyperp Medicament for preventive and/or therapeutic treatment of hyperp

1997-03-05

1999-11-09

Kulkosky, Peter F.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Aftertreated polymer

A61K 31785

Patent

active

059808810

ABSTRACT:
A medicament for preventive and/or therapeutic treatment of hyperphosphatemia which comprises a pharmaceutically acceptable anion exchange resin such as a 2-methylimidazole/epichlorohydrin copolymer, cholestyramine resin, or colestipol. The medicament is orally available and has lowering effect on blood phosphate concentration and reducing effect on urinary phosphate excretion, and is useful for the treatment of conditions caused by hyperphosphatemia including renal dysfunction and the like.

REFERENCES:
patent: 4412011 (1983-10-01), Kihara et al.
patent: 5380522 (1995-01-01), Day
patent: 5447726 (1995-09-01), Nomura
patent: 5496545 (1996-03-01), Holmes-Farley et al.
Hagmaier et al., Helv. Chis. Acta., vol. 48, No. 3-4 (1981) pp. 421-424.
Burt et al., Uremia Invest., vol. 9, No. 1 (1986), pp. 35-44.
Grynpas et al., Life Support Syst., vol.; 4, No. suppl. 2 (1986) pp. 276-278.
Burt et al., J. Pharma. Sci., vol. 76, No. 5 (May 1987) pp. 379-383.

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