Medical device for delivering a water-insoluble therapeutic salt

Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Arterial prosthesis – Stent structure

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

623 12, A61F 206

Patent

active

060130997

ABSTRACT:
A device useful for localized delivery of a therapeutic material is provided. The device includes a structure including a porous material; and a water-insoluble salt of a therapeutic material dispersed in the porous material. The water-insoluble salt is formed by contacting an aqueous solution of a therapeutic salt with a heavy metal water-soluble salt dispersed throughout a substantial portion of the porous material. The porous material can be made of a polymer other than fibrin with fibrin incorporated into the pores, which can be the only layer of polymeric material on the medical device (e.g., stent). A new method for preparing a porous polymer material on a medical device.

REFERENCES:
patent: 3105492 (1963-10-01), Jeckel
patent: 3425418 (1969-02-01), Chvapil et al.
patent: 3451996 (1969-06-01), Sumyk et al.
patent: 3523807 (1970-08-01), Gerendas
patent: 3549409 (1970-12-01), Dyck
patent: 3688317 (1972-09-01), Kurtz
patent: 4188188 (1980-02-01), Willner et al.
patent: 4229540 (1980-10-01), Coan
patent: 4229838 (1980-10-01), Mano
patent: 4321711 (1982-03-01), Mano
patent: 4540573 (1985-09-01), Neurath et al.
patent: 4548736 (1985-10-01), Muller et al.
patent: 4612337 (1986-09-01), Fox, Jr. et al.
patent: 4613665 (1986-09-01), Larm
patent: 4623539 (1986-11-01), Tunc
patent: 4680177 (1987-07-01), Gray et al.
patent: 4733665 (1988-03-01), Palmaz
patent: 4768507 (1988-09-01), Frischell et al.
patent: 4800882 (1989-01-01), Gianturco
patent: 4873308 (1989-10-01), Coury et al.
patent: 4886062 (1989-12-01), Wiktor
patent: 5010063 (1991-04-01), Piani et al.
patent: 5039529 (1991-08-01), Bergendal et al.
patent: 5059166 (1991-10-01), Frischell et al.
patent: 5061276 (1991-10-01), Tu et al.
patent: 5104860 (1992-04-01), Piani et al.
patent: 5342605 (1994-08-01), Illig
patent: 5352434 (1994-10-01), Illig et al.
patent: 5399318 (1995-03-01), Mancilla et al.
patent: 5464650 (1995-11-01), Berg et al.
patent: 5510077 (1996-04-01), Dinh et al.
patent: 5531735 (1996-07-01), Thompson
patent: 5541305 (1996-07-01), Yokota et al.
patent: 5554182 (1996-09-01), Dinh et al.
patent: 5571166 (1996-11-01), Dinh et al.
patent: 5591227 (1997-01-01), Dinh et al.
patent: 5599352 (1997-02-01), Dinh et al.
patent: 5609629 (1997-03-01), Fearnot et al.
patent: 5624411 (1997-04-01), Tuch
patent: 5679400 (1997-10-01), Tuch
patent: 5697967 (1997-12-01), Dinh et al.
patent: 5716981 (1998-02-01), Hunter et al.
patent: 5776184 (1998-07-01), Tuch
patent: 5843146 (1998-12-01), Slepian et al.
patent: 5848995 (1998-12-01), Walder
patent: B14733665 (1994-01-01), Palmaz
Dyck, "Inorganic Heparin Complexes for the Preparation of Nonthrombogenic Surfaces", J. Biomed. Mater. Res., 6, pp. 115-141 (1972).
Lincoff et al., "Intracoronary Stenting Compared with Conventional Therapy for Abrupt Vessel Closure Complicating Coronary Angioplasty", J. Am. Coll. Cardiol., 21, pp. 866-875, 1993.
Liu et al., "Porous polyurethane vascular prostheses with variable compliances", J. Biomed. Mater. Res., 26, pp. 1489 (1992).
McNair, "Using Hydrogel Polymers for Drug Delivery", Medical Device Technology, pp. 16-22, (1996).
"Photolink Surface Modifications Technical Bulletin: Heparin Coatings for Medical Devices", Brochure from BSI Surface Modification Sciences, (1994).
William D. Spotnitz et al., "Fibrin Glue from Stored Human Plasma. An Inexpensive and Efficient Method for Local Blood Bank Preparation", The American Surgeon, 53, 460-462 (1987).
Van Beusekom et al., "Synthetic polymers as an alternative to metal in stens? In vivo and mechnical behaviour of polyethylene-terephtalate", Circulation, 86 (supp. I), pp. I-731, No. 2912, 1992.
K. Whang et al., "A novel method to fabricate bioabsorable scaffolds", Polymer, 36:4, 837-842 (1995).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Medical device for delivering a water-insoluble therapeutic salt does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Medical device for delivering a water-insoluble therapeutic salt, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Medical device for delivering a water-insoluble therapeutic salt will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1458739

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.