Leukotriene antagonists

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...

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514438, 514457, 514544, 544335, 546335, 546337, 546342, 548253, 549 77, 549 79, 549401, 549496, 560 9, 560 11, 560 17, 560 18, 562429, 562431, 562432, A61K 3119

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053149181

ABSTRACT:
This invention relates to alkanoic acid compounds having phenyl and heteroarylthio substituents which are useful as leukotriene antagonists, processes for the preparation thereof, and pharmaceutical compositions containing such compounds.
This invention also relates to methods of treating diseases in which leukotrienes are a factor by administration of an effective amount of the above compounds or compositions.

REFERENCES:
patent: 4609744 (1986-09-01), Young et al.
patent: 4617407 (1986-10-01), Young et al.
Derwent Patent Abstract 84-014267/03 of Japanese Patent Appln. 58/206556A, published Dec. 1, 1983.
Derwent Patent Abstract 85-026589/05 of European Patent Appln. 132336A, published Jan. 30, 1985.
Chemical Abstracts 96(17): 143290n, (1981).
Chemical Abstracts 94(9): 64755y, (1981).

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