Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of...
Reexamination Certificate
2005-10-25
2005-10-25
Prouty, Rebecca (Department: 1652)
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
C435S194000, C435S252300, C435S320100, C536S023200
Reexamination Certificate
active
06958238
ABSTRACT:
The invention provides Dishevelled Associated Kinase polypeptides, which phosphorylate Dsh proteins involved in the Wnt/Wg signalling pathway. Isolated polynucleotides encoding DAK polypeptides are further provided, as are recombinant vectors, and host cells comprising the polynucleotides. Methods of using the polynucleotides and polypeptides of the invention are further aspects of the invention, including assays to detect agents which modulate DAK kinase activity. Further provided are methods of modulating pathways involved in control of cell proliferation.
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Sun Tian-Qiang
Williams Lewis T.
Borden Paula A.
Bozicevic Field & Francis LLP
Prouty Rebecca
The Regents of the University of California
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