Heteroaralkyl and heteroarylthioalkyl thiophenolic compounds as

Details Heteroaralkyl and heteroarylthioalkyl thiophenolic compounds as Heteroaralkyl and heteroarylthioalkyl thiophenolic compounds as

1994-10-25

1997-06-03

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514312, 546118, 546157, A61K 3144, A61K 3147, C07D47104, C07D215227

Patent

active

056355149

ABSTRACT:
Compounds of the formula: ##STR1## and the pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising a therapeutically-effective amount of the compounds or salts in combination with a pharmaceutically-acceptable carrier and methods for treating 5-lipoxygenase mediated conditions, inflammation-associated disorders and allergies.

REFERENCES:
patent: 4692532 (1987-09-01), Spivack et al.
patent: 4808644 (1989-02-01), Spivack et al.
patent: 4931444 (1990-06-01), Van Wauwe
patent: 5081253 (1992-01-01), Santilli
Delgado JN and Remers WA. Textbook of Organic Medicinal and Pharmaceutical Chemistry. Ninth Edition. p. 30.
S. A. Zaotova, et al. "Synthesis and Biological Activity of Substituted Sulfides of Indole and Benzofuran", Khim-Farm. Zh., 26 (1), 52-55. (1992).

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