Fluoroalkyl substituted benzoylguanidines

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

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Details

514634, 564162, 564183, 564230, A61K 31155, C07C23364, C07C27902

Patent

active

058695311

ABSTRACT:
Disclosed are 4-(2'-trifluoromethylethyl)benzoylguanidine and 3-methylsulfonyl-4-(2'-trifluoromethylethyl)benzoylguanidine. Also disclosed are pharmaceutical compositions and the use of the compounds in the treatment of disorders induced by ischemia.

REFERENCES:
patent: 3780027 (1973-12-01), Cragoe, Jr. et al.
patent: 5091394 (1992-02-01), Englert et al.
patent: 5373024 (1994-12-01), Lang et al.

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