Estrogen nucleus derivatives for use in inhibition of sex steroi

Details Estrogen nucleus derivatives for use in inhibition of sex steroi Estrogen nucleus derivatives for use in inhibition of sex steroi

1992-07-21

1993-04-20

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

540 83, 548494, 564171, 564172, 552510, 552528, 552536, 552538, 552540, 552626, C07J 4100, A61K 3156

Patent

active

052043371

ABSTRACT:
Novel compounds for the inhibition of sex steroid activity for the treatment of both androgen-related and estrogen-related diseases include for example 15- and 16-halo substituted compounds such as: ##STR1## The compounds are characterized by an estrogenic nucleus substituted with a substituent of the formula --R.sup.1 [B--R.sup.2 --].sub.x L--G wherein

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