Epipodophyllotoxin glucoside 4'-phosphate derivatives

Details Epipodophyllotoxin glucoside 4'-phosphate derivatives Epipodophyllotoxin glucoside 4'-phosphate derivatives

1989-12-14

1991-08-20

Griffin, Ronald W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 33, 536 171, 536 181, A61K 3170, C07H 1524

Patent

active

050414240

ABSTRACT:
Phosphate derivatives of 4'-demethylepipodophyllotoxin glucosides are novel antitumor agents and the salts thereof offer the pharmaceutical advantage of high water solubility.

REFERENCES:
patent: 3408441 (1968-10-01), Von Wartburg et al.
patent: 3524844 (1970-08-01), Keller-Juslen et al.
patent: 4564675 (1986-01-01), Kurabayashi et al.
Cancer Chemotherapy Reports, Part I (1975) 59:233-242.

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