Endothelin antagonist

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

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Details

C530S331000

Reexamination Certificate

active

06953780

ABSTRACT:
The instant invention relates to some tripeptide derivatives having activity against endothelin a process for preparing them, pharmaceutical composition containing the same and their use in prevention or treatment of some diseases associated with endothelin.

REFERENCES:
patent: 5260276 (1993-11-01), Cody et al.
patent: 5691315 (1997-11-01), Ishikawa et al.
patent: 0 548 441 (1993-06-01), None
patent: 7-228594 (1995-08-01), None
Itoh et al. A Novel Endothelin ETA Receptor Antagonist, BQ-485 . . . Biochemical And Biophysical Research Communications. Sep. 15, 1993, vol. 195, No. 2, pp. 969-975.
Spellmeyer et al,Bioorganic Medicinal Chemistry Letters, 3(4):519-524 (1993).

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