Derivative of nicotinic acid with amines

Details Derivative of nicotinic acid with amines Derivative of nicotinic acid with amines

1976-03-19

1977-05-03

Rotman, Alan L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602955A, 424266, C07D21356

Patent

active

040214354

ABSTRACT:
A novel thiazolidide ester of nicotinic acid is disclosed having the formula: ##STR1## The compound has the useful pharmacological activity of lowering cholesterol, free fatty acid and triglyceride plasma levels in cases of malfunctioning lipid metabolism.
A synthesis of the compound from nicotinoyl chloride hydrochloride or nicotinic acid is described as well as modes for the administration of the compound.

REFERENCES:
patent: 2647120 (1955-07-01), Williamson et al.
patent: 3086976 (1963-04-01), Borsy et al.
patent: 3268526 (1966-08-01), Newallis et al.

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