Chemokine α-6

Details Chemokine α-6 Chemokine α-6

2005-12-27

2005-12-27

Mertz, Prema (Department: 1646)

Drug, bio-affecting and body treating compositions

Lymphokine

C530S324000, C530S402000, C435S069500, C435S071100, C435S071200, C435S325000, C435S320100, C435S471000, C435S252300, C435S254110

Reexamination Certificate

active

06979443

ABSTRACT:
The present invention relates to a novel CKα-6 protein which is a member of the alpha chemokine family. In particular, isolated nucleic acid molecules are provided encoding the human CKα-6 protein. CKα-6 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of CKα-6 activity. Also provided are diagnostic methods for detecting CNS and immune system-related disorders and therapeutic methods for treating CNS and immune system-related disorders.

REFERENCES:
patent: 5236829 (1993-08-01), Farber
patent: WO95/14772 (1995-06-01), None
Strieter, R.M. et al., The Journal of Biol. Chem., vol. 270(45):27348-27357 (1995).
Angiolillo, A.L. et al., The Journal of Exp. Medicine, vol. 182:155-162 (1995).
PCT Search Report (PCT/US98/22513).
Harlow et al. (1988) Antibodies, A Laboratory Manual. Chapter 5, p. 76 Cold Spring Harbor Laboratory.
George et al. (1988) Macromolecular Sequencing and Synthesis. Chapter 12, pp. 127-149. Alan R. Liss, Inc. New York.
Cunningham et al. (1989) Science. vol. 244:pp1081-1085.
Hillier et al. (May 1997) EMBL EST Database. Accession No. AA410918.

Affiliated with

Also associated with

Rating

Chemokine α-6 does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Chemokine α-6, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Chemokine α-6 will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3477086