Anti-HIV pharmaceutical formulations

Details Anti-HIV pharmaceutical formulations Anti-HIV pharmaceutical formulations

1995-05-19

1997-09-23

Glass, Margaret W.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

514885, 514596, 514597, 514598, 514510, 514533, 514648, 514657, 514646, 514706, A61K 3174

Patent

active

056701438

ABSTRACT:
The preferred oligomers of the present invention are polyureas, polycarbonates, polyesters or polyamides having a number average molecular weight of <10,000. These oligomers are water-soluble, have a rigid backbone, have recurring units coupled by carbonyl linking moieties which have anionic groups, display predominantly linear geomentry such that regular spacing between anionic groups exists in an aqueous medium, and are pharmaceutically-acceptable. The oligomers are useful for the treatment and/or diagnosis of AIDS and ARC.

REFERENCES:
patent: 2833744 (1958-05-01), Neher
patent: 3528949 (1970-09-01), Rutledge
patent: 3839294 (1974-10-01), Manos
patent: 4312855 (1982-01-01), Grand
patent: 4604404 (1986-08-01), Munson
patent: 4783446 (1988-11-01), Neushul
patent: 4824916 (1989-04-01), Kershner et al.
patent: 4895660 (1990-01-01), Kershner et al.
patent: 4966894 (1990-10-01), Herr et al.
patent: 5384119 (1995-01-01), Janusz
patent: 5424063 (1995-06-01), Cardin et al.
patent: 5460807 (1995-10-01), Cardin et al.
patent: 5571505 (1996-11-01), Cardin et al.
Vandenberg E.J. et al., Polymeric Matericals Science and Engineering, vol. 57, Fall Meeting 1987, pp. 139-143.
R.M. Ottenbrite, ACS Symposium Series #186, pp. 205-220 (1982) "The Antitumor and Antiviral Effects of Polycarboxyl-ic Acid Polymers".
European Chem. News, p. 17(Jul. 30, 1990).
Ahmed, et al., Antiviral Chemistry & Chemotherapy, (1995) 6(1), 34-42, "Potent Inhibition of Herpes Simplex Virus by MDL101028 a Novel Biphenyl Disulphonic Acid Co-polymer".
Antiviral Research, 18(1992), Sulfonic acid polymers as a new class of human immunodefic-ciency virus inhibitors, Prem Mohan, et al., pp. 139-150.
Komp et al, Chemical Abstracts vol. 110 Abstract No. 33727k (1989).
Cardin et al., "Stilbene Disulfonic Acids. CD4 Antagonists that Block human immunodeficiency Virus Type-1 Growth at Multiple Stages of the Viral Like Cycle" J. Biol. Chem (1991), 266(20), 13355-63.
Hofferek et al., Chemical Abstracts vol. 114: 180333q (1990).
Taylor et al, "Potent Inhibition of Human Immunodeficiency Virus (HIV) by MDL 101028, a Novel Supphonic Acid Polymer".
Berge et al., J Pharm. Sciences 66 (1), pp. 1-19.
Antiviral Research, 18 (1992), Sulfonic acid polymers as a new class of human immunodefi-ciency virus inhibitors, Prem Mohan, et al., pp. 139-150.

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