Aldose reductase inhibition by .gamma.-oxo-8-fluoranthenebutanoi

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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A61K 3119

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active

043615821

ABSTRACT:
Disclosed are new methods of using .gamma.-oxo-8-fluoranthenebutanoic acid, or a therapeutically acceptable salt thereof with an organic or inorganic base for the treatment of complications associated with diabetes mellitus. The compound inhibits lens aldose reductase in a diabetic mammal.

REFERENCES:
patent: 2560425 (1951-07-01), Fancher
patent: 3821383 (1974-06-01), Sestanj et al.
Gastroenterology, 37 735 (1959).

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