Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-05-31
1997-04-29
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514383, 548255, 5482662, A61K 31475, C07D40102
Patent
active
056249446
ABSTRACT:
6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz[cd]indoles are provided which are useful in modifying the function of serotonin in mammals.
REFERENCES:
patent: 3336307 (1967-08-01), Shen
patent: 3671541 (1972-06-01), Bormann et al.
patent: 3674801 (1972-07-01), Bormann et al.
patent: 4057560 (1977-11-01), Bormann et al.
patent: 4110339 (1978-08-01), Bach et al.
patent: 4252803 (1981-02-01), Webb
patent: 4282240 (1981-08-01), Baldwin et al.
patent: 4447438 (1984-05-01), Ledelc et al.
patent: 4576959 (1986-03-01), Flaugh
patent: 4576969 (1986-03-01), Echigo et al.
patent: 4745126 (1988-05-01), Leander
patent: 4977172 (1990-12-01), Johnson et al.
patent: 4983622 (1991-01-01), Flaugh
patent: 5039820 (1991-08-01), Kress et al.
patent: 5204340 (1993-04-01), Flaugh et al.
patent: 5212319 (1993-05-01), Kress et al.
patent: 5229410 (1993-07-01), Flaugh et al.
patent: 5266571 (1993-11-01), Amer
patent: 5397779 (1995-03-01), Kress et al.
Flaugh, et al., J. Med. Chem., 1988, 31, 1746-1753.
Kruse, et al., J. Org. Chem., 49, 4761-4768 (1984).
Bach, et al., J. Med. Chem., 23, 481-491 (1980).
Derwent Abstract 57337.
Haefliger, et al., Tet. Lett., 25, No. 3, 289 (1984).
Chemical Abstracts 107, 39610b for JP62-63,567.
Glennon, J. Med. Chem., 30, 1 (1987).
T.W. Greene, Protective Group in Organic Synthesis, John Wiley and Sons (1981) Chapter 7.
J.W. Barton, Protective Group in Organic Synthesis, McOmie, ed., Plenum Press (1973) Chapter 2.
Schoenberg, et al., J. Org. Chem., 39, p. 3327 (1974).
Schoenberg, et al., J. Org. Chem., 39, p. 3318 (1974).
Tetrahedron Letters 21, 4061 (1980).
Nichols, et al., Org. Prep. & Proc. Int., 9, 277 (1977).
Leanna, et al., Tet. Lett., 30, 3935 (1989).
O. Mitsunobu, Synthesis, Jan. 1981, p. 1.
J.P. Freemen, et al., Synthesis, Dec. 1974, p. 894.
Sugi, et al., Bull. Chem. Soc. Jap., 43, p. 1489 (1970).
Morrison & Boyd, Chapter 22, Organic Chemistry, 3rd Ed. (1973).
Wong, et al., J. Neural Transm., 71, 207-218 (1988).
Wong, et al., J. Neural Transm., 64, 251-269 (1985).
Heydrich, et al., J. Clin. Psych., 51(4) [Supp], 5 (1990).
Ray W. Fuller, Adv. in Drug. Res., 17, 349 (1988).
Sacxena, et al., J. Card. Pharm., 15, [Supp 7], 517 (1990).
Burger, Ed. Medicinal Chemistry 2d Ed. Interscience, NY, 42 (1960).
Dorland's Illustrated Medical Dictionary 26th Ed. Saunders, Philadelphia, 1981 p. 1193.
Booher Richard N.
Lawhorn David E.
Paget, Jr. Charles J.
Schaus John M.
Daus Donald G.
Eli Lilly and Company
Palmberg Arleen
Taylor Douglas J.
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