16-Fluoro prostaglandin E.sub.1 analogs

Details 16-Fluoro prostaglandin E.sub.1 analogs 16-Fluoro prostaglandin E.sub.1 analogs

1975-02-21

1976-07-13

Gerstl, Robert

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260211R, 2602472R, 260268R, 26029365, 2603262, 2604299, 260439R, 260448R, 260468D, 260488R, 2605011, 26050115, 26050117, 2605012, 260514D, C07C 6138, C07C 6974

Patent

active

039693775

ABSTRACT:
Prostaglandin-type compounds with one or two fluoro substituents at the C-16 position are disclosed, with processes for making them. These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, labor inducement at term, and wound healing.

REFERENCES:
nakanishi et al., JACS, 81 5259, (1959).

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