Pharmaceutically active 9-chloroprostaglandins

Details Pharmaceutically active 9-chloroprostaglandins Pharmaceutically active 9-chloroprostaglandins

1991-11-15

1993-04-20

Gerstl, Robert

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514573, 560121, 562503, C07C17700, A61K 31557

Patent

active

052043711

ABSTRACT:
Compounds of the formula ##STR1## wherein the 9-chlorine atom can be in the .alpha.-or .beta.-position,

REFERENCES:
patent: 4192799 (1988-03-01), Fitzpatrick
patent: 4444788 (1984-04-01), Skuballa et al.
Muchowski, "Synthesis and Bronchial Dilator Activity," Chemistry, Biochemistry & Pharmacological Activity of Prostanoids, Pergamon Press (Jul. 10-14, 1978).
Binder et al., "16-Aryloxprostaglandins: A New Class of Ptent Luteolytic Agent," Prostaglandins, vol. 6, No. 1, pp. 87-91 (Apr. 10, 1974).
Corey et al., "Total Synthesis of Prostaglandins F.sub.2 and E.sub.2 as the Naturally Occurring Forms," J. of the Amer. Chem. Soc., 92:2, pp. 397-398 (Jan. 28, 1970).
Arroniz, Prostaglandius, 16, 47 (1978).

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