Tetrapeptide regulating blood glucose level in diabetes...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

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Details

C530S330000

Reexamination Certificate

active

07491703

ABSTRACT:
The invention refers to the field of medicine and can be applied as a substance capable of regulating glucose level while treating and preventing diabetes mellitus. There is proposed a biologically active new tetrapeptide lysyl-glutamyl-aspartyl-tryp-tophane of general formula Lys-Glu-Asp-Trp-NH2capable of regulating the glucose level, and pharmacological substance containing an effective amount of tetrapeptide lysyl-glutamyl-aspartyl-tryptophane of the general formula Lys-Glu-Asp-Trp-NH2. There is proposed the method of prevention and/or treatment of the diabetes mellitus, which consists in administering to a patient of the pharmacological substance, containing as an active peptide agent an effective amount of Lys-Glu-Asp-Trp-NH2tetrapeptide in doses of 0.1-30 μg/kg of the body weight at least once a day for a period necessary for attaining a therapeutic effect.

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Schatz et al. Why Can't We Prevent Type 1 Diabetes. Diabetes Care, Dec. 2003. vol. 26, No. 12, pp. 3326-3328.
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