Test for Johne's disease

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives


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435 6, 435863, 436501, 436811, 935 78, C07H 2104, C12N 1500, C12Q 168, C12R 132




A test to diagnose the presence of Johne's disease is disclosed. In one aspect it involves using a DNA segment that will hybridize to M. paratuberculosis but not to other bacteria typically found in bovine feces. Another aspect of the invention is providing a process for breaking the cell wall of mycobacteria using dense beads in the presence of phenol.

patent: 4358535 (1982-11-01), Falkow et al.
patent: 4362867 (1982-12-01), Paddock
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