Stabilized plasminogen activator precursor and method of produci

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Stablizing an enzyme by forming a mixture – an adduct or a...

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435212, 435215, C12N 996, C12N 972

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active

050752308

ABSTRACT:
A plasminogen activator precursor obtainable from a serum-free culture fluid of human kidney cells is stabilized by adding to its solution poly-C1-C5-alkylene glycols, polyethylene-polyoxypropylene copolymers, mandelic acid salts, triethanolamine, acid addition salts of acetylglycillysine methyl ester, guanidine salts, thiocyanic acid salts, alkali metal iodides or serine.

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Nielsen et al., Biochemistry 1982, vol. 21, pp. 6410-6415.

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