Process for the preparation of ibuprofen

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound


Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0


435141, 435196, 435280, 4352521, 4352525, 435823, 435882, C12P 700, C12N 900




A process is provided for the preparation of ibuprofen enriched in R isomer, which comprises subjecting an ester of ibuprofen, to the action of a micro-organism or substances derived thereof, that will stereoselectively hydrolyse the ester to form ibuprofen predominantly having R configuration.

patent: 4886750 (1989-12-01), Bertola et al.
"Asymmetric Hydrolysis of (.+-.)-alpha-substituted Carboxylic Acid Esters with Microorganism," Agricultural and Biological Chemistry, vol. 45, No. 6, (1981) pp. 1389-1392.
Bergey's Manual of Systematic Bacteriology, vols. 1 & 2, ed. Krieg, pp. 269-271 (vol. 1), pp. 1015-1019 and 1131 (vol. 2).


Say what you really think

Search for the USA inventors and patents. Rate them and share your experience with other people.


Process for the preparation of ibuprofen does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the preparation of ibuprofen, we encourage you to share that experience with our community. Your opinion is very important and Process for the preparation of ibuprofen will most certainly appreciate the feedback.

Rate now


Profile ID: LFUS-PAI-O-1248899

All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.