Process for producing an optically active 2-arylpropionic acid

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound

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435136, 435141, 435280, 435822, 435911, C12P 762, C12P 740, C12P 4100, C12R 100

Patent

active

050432745

ABSTRACT:
A process for the preparation of S-2-(6-methoxy-2-naphthyl)propionic acid or a pharmaceutically acceptable salt or ester thereof, which comprises supplying R-2-(6-methoxy-2-naphthyl)-propionic acid or a pharmaceutically acceptable salt or ester thereof, to a microorganism having a stereospecific inverting enzyme system, or an extract of the microorganism containing said enzyme system, capable of converting the R enantiomer to the corresponding S enantiomer.

REFERENCES:
patent: 4661628 (1987-04-01), Cannata et al.
patent: 4886750 (1989-12-01), Bertola et al.

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